Research we are currently funding:
This study will compare current standard PCV treatment to oral temozolomide chemotherapy combined with with radiation, for effectiveness with fewer side effects.
A synthetic retinoid (a compound derived from vitamin A) has been found to acts powerfully against Diffuse intrinsic pontine gliomas (DIPG) cells.
Dr Khasraw is looking at whether adding a drug to this treatment regime can make the chemo-radiotherapy more effective.
Neuroblastoma accounts for around 15% of deaths from cancer in children. Dr MacKenzie and her team have found that blocking a certain protein can kill neuroblastoma cells.
Impact we've achieved with our research:
This research has provided a groundbreaking insight into the relationship between the protein dyskerin and neuroblastoma, a deadly childhood cancer.
Dr Megan Chircop's team have found new compounds that can target the deadliest type of malignant brain tumour, glioblastoma multiforme.
A novel approach to shutting down the energy supply in cancer cells has led to highly promising treatments that are already undergoing successful trials in people with solid cancer tumours.